OWC 128GB (2x64GB) DDR4 3200 CL22 2Rx4 ECC Registered DIMM Kit for HP SimpliVity 380 Gen10

HP SimpliVity 380 Gen10 upgrade

This 128GB kit supplies two 64GB DDR4 3200 CL22 ECC registered DIMMs built for the HP SimpliVity 380 Gen10 server. Each module runs at 1.2V using a 288-pin 2Rx4 layout and meets JEDEC PC4-25600 timing. The registered design with error correction targets virtualisation hosts and hyper-converged workloads that demand data integrity over raw latency.

Replaces HP P43170-B21 and P06035-B21

The kit replaces original HP part numbers P43170-B21 P06035-B21 P06035-H21 P07650-B21 P07650-H21 P07650-K21 P25205-B21 with equivalent capacity and speed. The jump is worth it when expanding a cluster node beyond its factory DIMM count or when consolidating smaller modules to free slots for future growth. Mixing with unbuffered or load-reduced ECC memory is not supported by the platform.

128GB headroom for dense VMs

Two 64GB ranks deliver 128GB total capacity, letting a single node host dozens of memory-heavy virtual machines or large in-memory databases. The 3200 MT/s rate and CL22 latency keep throughput steady under sustained load. Headroom runs out when workloads exceed the server's maximum DIMM slots or when applications need load-reduced DIMMs for higher per-slot density.