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ATX motherboard with silver heatsinks and black PCB

ASUS

ASUS PRIME TRX40-PRO S AMD motherboard

SKU CH-CCKE-JJQM2

ATX board for third-generation AMD Ryzen Threadripper CPUs with eight DDR4 slots supporting up to 256GB, three PCIe 4.0 x16 slots, three M.2 sockets, eight SATA ports.

  • CPU Socket TypesTRX4
  • CPU TypeAMD sTRX4
  • ChipsetAMD TRX40
  • Number of Memory Slots8x288pin (DDR4)
  • Memory StandardDDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.
  • Maximum Memory Supported256GB
  • Supports 3rd Gen Ryzen Threadripper CPUs via sTRX4 socket
  • Eight DDR4 slots deliver up to 256 GB quad-channel memory
  • Three PCIe 4.0 x16 SafeSlots for multi-GPU or add-in cards
  • Three M.2 sockets plus eight SATA 6Gb/s ports for high-capacity storage
  • Intel I211AT LAN and Realtek ALC1220 8-channel audio for wired networking and sound

sTRX4 Threadripper Workstation Board

The ASUS PRIME TRX40-PRO S is an ATX motherboard built around the AMD TRX40 chipset for 3rd Gen Ryzen Threadripper processors. It targets professionals who need high core counts and large memory capacity in a standard form factor.

Eight DDR4 Slots Up to 256GB

Creators and engineers running memory-intensive workloads benefit from eight 288-pin slots supporting quad-channel DDR4 up to 4666 MHz O.C. and 256GB total. Builds requiring ECC UDIMM support are covered. Systems needing registered ECC or more than eight DIMMs should choose a WRX80 platform instead.

Three PCIe 4.0 x16 SafeSlots

The board provides three reinforced PCIe 4.0 x16 slots wired for x16/x16/x16 operation with recommended 3rd Gen Threadripper CPUs. This layout decides whether multi-GPU compute or multiple high-bandwidth add-in cards will fit without sharing bandwidth.

Highlights

  • Supports 3rd Gen Ryzen Threadripper CPUs via sTRX4 socket
  • Eight DDR4 slots deliver up to 256 GB quad-channel memory
  • Three PCIe 4.0 x16 SafeSlots for multi-GPU or add-in cards
  • Three M.2 sockets plus eight SATA 6Gb/s ports for high-capacity storage
  • Intel I211AT LAN and Realtek ALC1220 8-channel audio for wired networking and sound

Specifications

BrandASUS
SeriesTRX40
ModelPRIME TRX40-PRO S
CPU Socket TypesTRX4
CPU TypeAMD sTRX4
ChipsetAMD TRX40
Number of Memory Slots8x288pin (DDR4)
Memory StandardDDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.)/ 4133(O.C.)/ 3800(O.C.)/ 3733(O.C.)/ 3466(O.C.)/ 3400(O.C.)/ 3200/ 2933/ 2800/ 2666/ 2400/ 2133 MHz ECC and non-ECC, Un-buffered Memory
Maximum Memory Supported256GB
Channel SupportedQuad Channel
PCI Express 4.0 x163rd Gen AMD Ryzen Threadripper Desktop Processors - 3 x PCIe 4.0 x16 Safeslots (supports x16/x16/x16 mode)* * Recommend you to install add-on cards on (PCIEX16_1 and PCIEX16_2) or (PCIEX16_1 and PCIEX16_3) to enjoy 2 way SLI or CrossFireX.
PCI Express x4AMD TRX40 chipset: 1 x PCIe 4.0 (x4 mode)
Other Slots1 x M.2 Socket (Key E), supports type 2230 PCIe Wi-Fi/BT module* * The Wi-Fi/BT module is purchased separately
Serial ATA (SATA)8 x SATA 6Gb/s
M.23rd Gen AMD Ryzen Threadripper Series Desktop processors: 2 x M.2 Socket 3, with M key, type 2242/2260/2280/22110 storage devices support (PCIe 4.0 x4 mode) AMD TRX40 chipset: 1 x M.2 Socket 3, with vertical M key, type 2242/2260/2280/22110 storage devices support (SATA & PCIe 4.0 x4 mode)
SATA RAID0/1/10
Audio ChipsetRealtek ALC S1220 High Definition Audio CODEC featuring Crystal Sound 3
Audio Channels8 Channels
LAN ChipsetIntel i211AT
Max LAN Speed1Gbps
Back I/O Ports1 x LAN (RJ45) port(s) 4 x USB 3.2 Gen 2 (teal blue) (3 x Type-A + 1 x Type-C) (one port can be switched to USB BIOS FlashBack) 6 x USB 3.2 Gen 1 (blue) 1 x Optical S/PDIF out 5 x Audio jack(s) 1 x USB BIOS FlashBack Button(s)
Onboard USB1 x USB 3.2 Gen 2 front panel Type-C connector 2 x USB 3.2 Gen 1 connectors support additional 4 USB ports (19-pin) 2 x USB 2.0 connectors support additional 4 USB ports
Other Connectors1 x 4-Pin W_PUMP+ connector 1 x 4-Pin AIO_PUMP fan connector 1 x 4-Pin CPU Fan connector 1 x 4-Pin CPU_OPT fan connector 1 x 3-pin Chipset fan connector 3 x 4-Pin Chassis Fan connectors 1 x 2-pin Thermal sensor header 2 x Aura Addressable Gen2 headers 2 x Aura RGB headers 1 x NODE connector 1 x Front panel audio connector (AAFP) 1 x System panel connector with FlexKey 1 x Q_Code 1 x Clear CMOS header 1 x Power-on button
Form FactorATX
LED LightingRGB
Dimensions (W x L)12.0" x 9.6"
Power Pin1 x 24-pin EATX Power connector(s) 2 x 8-pin ATX 12V Power connector(s)
Windows 11Supported
FeaturesMulti-GPU Support: Supports NVIDIA Quad-GPU SLI Technology Supports NVIDIA 2-Way SLI Technology Supports AMD Quad-GPU CrossFireX Technology Supports AMD 2-Way CrossFireX Technology Special Features: ASUS Dual Intelligent Processors 5-Way Optimization by Dual Intelligent Processors 5: - 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Expert 4, and Turbo App ASUS SafeSlot - Protect your graphics card Investment AURA: - Aura RGB Strip Headers - Aura Lighting Effects Synchronization with compatible ASUS ROG devices - Addressable Gen 2 Header ASUS Exclusive F

Questions about this item

Will this board take my existing DDR4 ECC modules?

Yes, the eight 288-pin slots accept both ECC and non-ECC un-buffered DDR4 up to 256 GB total in quad-channel mode.

How many full-length graphics cards can run at x16 speed?

Three PCIe 4.0 x16 SafeSlots support x16/x16/x16 mode with a 3rd Gen Threadripper CPU; using the first and second or first and third slots is recommended for two cards.

What M.2 drives fit the three onboard slots?

Two CPU-linked slots take 2242, 2260, 2280 and 22110 M-key drives at PCIe 4.0 x4; the chipset slot is a vertical M-key 2280/22110 also at PCIe 4.0 x4.

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