We take cryptocurrency — so the coins you hold can buy real hardware.Pay in crypto, spend it on real hardware. Free insured shipping worldwide over $399. Plain, unbranded boxes, sent from Germany.Free insured shipping over $399. Your rate is locked for 30 minutes once checkout opens.Rate locked 30 minutes. Every item sealed, serial-checked and covered by a 24-month warranty.Sealed, 24-month warranty.

Saved items Sign in
Large EEB motherboard with twelve memory sockets and four full-length PCIe slots, dark metallic finish with angular heatsinks

ASUS

ASUS ROG DOMINUS EXTREME Intel C621 3647 LGA EEB Motherboard

SKU CH-538C-CTAGG

Supports Xeon W-3175X with 12 DDR4 slots up to 192GB, four PCIe 3.0 x16, dual 10Gbps and 1Gbps LAN, Wi-Fi 802.11 and SupremeFX audio

  • CPU Socket TypeLGA 3647
  • CPU TypeSupport to Xeon W-3175X
  • ChipsetIntel C621
  • Number of Memory Slots12x288pin (DDR4)
  • Memory StandardSupport up to DDR4 4200(O.C.)
  • Maximum Memory Supported192GB
  • Supports Xeon W-3175X for extreme workstation performance
  • 12 DDR4 slots enable up to 192 GB six-channel memory
  • Four PCIe 3.0 x16 slots offer flexible multi-GPU configurations
  • Dual 10 Gbps and 1 Gbps LAN plus Wi-Fi 802.11 for high-speed networking
  • SupremeFX S1220 audio delivers 120 dB SNR playback and 113 dB SNR recording

Designed for Xeon W-3175X workstations

This EEB motherboard pairs the Intel C621 chipset with an LGA 3647 socket to support the Xeon W-3175X processor. Twelve 288-pin slots provide six-channel DDR4 memory up to 192 GB with XMP 3.0 and ECC capability. Dual 10 Gbps and 1 Gbps LAN plus Intel Wireless-AC 9260 give high-speed wired and wireless connectivity. SupremeFX S1220 audio delivers 120 dB SNR playback and 113 dB SNR recording.

Replaces standard ATX workstation boards

The EEB form factor adds four PCIe 3.0 x16 slots configurable as x16/x16/x16 or x16/x8/x16/x8 alongside a legacy PCI slot. Six SATA 6 Gb/s ports and two ROG DIMM.2 modules accept M-key drives in 2242, 2260, 2280 and 22110 lengths running at PCIe 3.0 x4. This density suits multi-GPU compute, large memory capacity and high-speed storage arrays that exceed typical ATX limits.

Verify EEB case clearance and power delivery

Confirm the chassis accommodates the EEB dimensions and provides sufficient 12 V current for the CPU and six-channel memory. Ensure the power supply includes the required EPS connectors for the 3647 socket. Check that cooling solutions clear the DIMM.2 modules and U.2 connectors. Validate operating-system support for the AQC107 and I219-LM network controllers and the S1220 audio codec.

Highlights

  • Supports Xeon W-3175X for extreme workstation performance
  • 12 DDR4 slots enable up to 192 GB six-channel memory
  • Four PCIe 3.0 x16 slots offer flexible multi-GPU configurations
  • Dual 10 Gbps and 1 Gbps LAN plus Wi-Fi 802.11 for high-speed networking
  • SupremeFX S1220 audio delivers 120 dB SNR playback and 113 dB SNR recording

Specifications

BrandASUS
ModelROG DOMINUS EXTREME
CPU Socket TypeLGA 3647
CPU TypeSupport to Xeon W-3175X
ChipsetIntel C621
Number of Memory Slots12x288pin (DDR4)
Memory StandardSupport up to DDR4 4200(O.C.)
Maximum Memory Supported192GB
Channel SupportedSix Channel
Memory Performance ProfileIntel XMP 3.0
ECC SupportedYes
PCI Express 3.0 x164 x PCIe 3.0 x16 (x16/x16/x16, x16/x8/x16/x8)
PCI Slots1 x PCI Slot
Serial ATA (SATA)6 x SATA 6Gb/s
M.2Intel Xeon W-3175X Processor:
2 x ROG DIMM.2 Module support (CPU_DIMM.2), with M key, type 2242/2260/2280/22110 storage devices support (PCIE 3.0 x4 mode)*
2 x U.2 connector*
* The PCIEX16_2 shares bandwidth with the DIMM.2_2_2, U.2_2, DIMM.2_1_1 and DIMM.2_1_2 slots.
* The PCIEX16_3 shares bandwidth with the DIMM.2_2_1 and U.2_1 slots.
* The PCIEX16_4 shares bandwidth with the DIMM.2_1_1 and DIMM.2_1_2 slots.
Audio ChannelsROG SupremeFX 8-Channel High Definition Audio CODEC S1220
- Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking
- High quality120dBSNR stereo playback outputand113dBSNR recording input
- SupremeFX Shielding Technology
- Supports up to 32-Bit/192kHz playback *2
Audio Feature :
- Optical S/PDIF out port(s) at back panel
- Sonic Radar III
- Sonic Studio III + Sonic Studio Link
LAN ChipsetAQUANTIA AQC107
Second LAN ChipsetIntel I219-LM
Max LAN Speed10Gbps + 1Gbps
Wireless LANIntel Wireless-AC 9260
Wi-Fi 802.11 a/b/g/n/ac
Supports dual band frequency 2.4/5 GHz
Supports MU-MIMO
Supports channel bandwidth: HT20/HT40/HT80/HT160. Up to 1.73Gbps transfer speed
BluetoothBluetooth 5.0
Back I/O Ports2 x USB 3.2 Gen 2 (black)Type-C,
2 x USB 3.2 Gen 2 (red)Type-A
1 x USB BIOS FlashBack Button(s)
8 x USB 3.2 Gen 1 (blue)
5 x LED-illuminated audio jacks
1 x Aquantia AQC-107 10G LAN port
1 x Optical S/PDIF out
1 x Clear CMOS button(s)
1 x ASUS Wi-Fi Module
Anti-surge LAN (RJ45) port
RJ451 x RJ45
USB 3.11 x USB 3.1
Onboard USB2 x USB 3.1 Gen 1(up to 5Gbps) connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s)
2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s)
Other Connectors2 x Aura Addressable Strip Header(s)
1 x VROC_HW_Key
2 x LED connectors (Back I/O cover, PCH, OLED)
2 x Chassis Fan connector(s) (2 x 4-pin)
1 x PCH_FAN (1 x 3-pin)
2 x HS_FAN (2 x 4-pin)
2 x W_PUMP+ connector (2 x 4-pin)
1 x WB_SENSOR (1 x 9-pin)
1 x Thunderbolt header(s)
2 x 6-pin EATX 12V Power connector
2 x 24-pin EATX Power connector(s)
4 x 8-pin EATX 12V Power connectors
1 x 6-pin EZ_PLUG Power connector(s)
13 x ProbeIt Measurement Points
1 x BIOS Switch button(s)
2 x U.2 connector
1 x PCIe x16 lane switch
2 x T_Sensor Connector
1 x USB 3.1 Gen 2 front panel connector
2 x DIMM.
BIOS Feature2 x 128 Mb Flash ROM, UEFI AMI BIOS, PnP, SM BIOS 3.1, ACPI 6.1, Multi-language BIOS, ASUS EZ Flash 3, CrashFree BIOS 3, Secure Erase, User Profile, F11 EZ RAID Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen, , F4 AURA ON/OFF and F9 Search
Form FactorEEB
Dimensions (W x L)14.0" x 14.0"
FeaturesMulti-GPU Support:
Supports NVIDIA 4-Way SLI Technology
Supports NVIDIA 3-Way SLI Technology
Supports NVIDIA 2-Way SLI Technology
Supports AMD 4-Way CrossFireX Technology
Supports AMD 3-Way CrossFireX Technology
Supports AMD 2-Way CrossFireX Technology
USB BIOS FlashBack
Clear CMOS button
- PCIe x16 Lane Switch
ProbeIt
ROG DIMM.2 module with heatsink
ROG Aluminum heatsink cover
Extreme Engine Digi+ :
- MicroFine Alloy Chokes
- 10K Black Metallic Capacitors
ROG Extreme OC kit :
- Safe Boot button
- Slow Mode
- LN2 Mode
ROG Patented Pre-mounted I/O Shield
ROG Exclusive Software
- RAMCa
Package ContentsAccessories:
User's manual
1 x ROG logo plate sticker
4 x M.2 Screw Package
1 x CPU installation tool
1 x ASUS 2T2R dual band Wi-Fi moving antennas (Wi-Fi 802.11 a/b/g/n/ac compliant)
1 x Fan Extension Card II (6 x 4-pin Chassis Fan connectors, 3 x RGB headers, 3 x 2-pin Thermal sensor header)
1 x Fan Extension Card II power cable
1 x Fan Extension Card II NODE connector cable
1 x Fan Extension Card II screw package
1 x SLI HB BRIDGE (2-WAY-L)
1 x Q-Connector
1 x ROG Logo Sticker(s)
1 x Extension Cable for RGB strips (80cm)
1 x Extension cable for Addressable LED
3 x Thermistor cable

Questions about this item

What size case and power connectors does the EEB form factor and 12 memory slots require?

The EEB board needs a chassis that accepts the larger EEB footprint and a PSU with a 24-pin ATX plus two 8-pin EPS connectors to feed the 12 DDR4 slots and CPU.

Which slot does the ROG DIMM.2 module plug into and what step is often missed?

Insert the ROG DIMM.2 module into a DDR4 DIMM socket, not an M.2 slot, then enable the CPU_DIMM.2 option in BIOS so the 2242/2260/2280/22110 drives are detected.

When should the Wi-Fi 9260 antennas be re-seated or the module swapped?

Re-seat the external antennas if 2.4/5 GHz signal drops or 1.73 Gbps throughput falls; replace the Intel Wireless-AC 9260 module if firmware updates no longer restore link stability.

Also in this aisle

People compared these

Same shelf, same checkout — eight coins and a 30-minute rate lock.