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Black mid-tower gaming desktop with RGB lighting and 360mm liquid cooler visible

MSI

MSI MAG PANO M100R Core Ultra 5 250KF RTX 5080 32GB 4TB Liquid Cooled Gaming PC

SKU CH-T9B6-MBY4S

An 18-core Intel Core Ultra 5 250KF and NVIDIA RTX 5080 with 16 GB GDDR7 power 4K gaming, cooled by a 360 mm liquid loop and backed by 32 GB DDR5 plus 4 TB NVMe storage

  • TypeGaming & Entertainment
  • Form FactorDIMM 288-pin
  • AI FeaturesAI Ready
  • UsageConsumer
  • ColorBlack
  • ProcessorCore Ultra 5 250KF

CPU Intel Core Ultra 5 250KF

Video Card GeForce RTX 5080

Memory|Storage 32GB DDR5|4TB SSD

  • 18-core Core Ultra 5 250KF hits 5.3 GHz for fast compute
  • RTX 5080 with 16 GB GDDR7 drives high-frame-rate 4K gaming
  • 360 mm liquid cooler keeps temperatures low under load
  • 4 TB NVMe SSD stores a large library with quick access
  • 32 GB DDR5 and 1000 W supply give headroom for heavy multitasking

Liquid-cooled Intel Core Ultra 5 250KF desktop

This MSI gaming PC pairs an 18-core processor with a 360 mm liquid cooler and a GeForce RTX 5080 graphics card. It ships with 32 GB of DDR5 memory and a 4 TB NVMe SSD, running Windows 11 Home from a 1000 W power supply.

Builders who want a ready-to-game system

The completed chassis, integrated 2.5G Ethernet, Wi-Fi and RGB lighting suit buyers who prefer not to assemble parts themselves. Shoppers needing a smaller form factor, a different GPU tier or a lower-wattage power supply should consider other configurations.

RTX 5080 with 16 GB GDDR7 video memory

The graphics card provides 16 GB of GDDR7 memory for high-resolution gaming and content-creation workloads. Buyers whose applications require more video memory than this card supplies will need to look at alternative hardware.

Highlights

  • 18-core Core Ultra 5 250KF hits 5.3 GHz for fast compute
  • RTX 5080 with 16 GB GDDR7 drives high-frame-rate 4K gaming
  • 360 mm liquid cooler keeps temperatures low under load
  • 4 TB NVMe SSD stores a large library with quick access
  • 32 GB DDR5 and 1000 W supply give headroom for heavy multitasking

Specifications

BrandMSI
TypeGaming & Entertainment
Form FactorDIMM 288-pin
AI FeaturesAI Ready
UsageConsumer
ColorBlack
ProcessorCore Ultra 5 250KF
Processor Main Features64 bit 18-Core Processor
Memory32 GB
GraphicsRTX 5080
AudioSound card - Integrated
Ethernet2.5G Ethernet
Wireless CardYes
Power Supply1000W
CaseMSI MAG PANO M100R
Cooling SystemLiquid Cooling
Operating SystemWindows 11 Home
Windows 11Ready
Special FeaturesRGB Lighting
ChipsetIntel LGA 1851
Motherboard NameMSI LGA 1851 Motherboard WIFI DDR5
CPU TypeIntel Core Ultra 5 Series 2
Installed Qty1
Max Supported Qty1
CPU NameIntel Core Ultra 5 250KF
CPU Base Frequency5.3GHz
CPU Socket TypeLGA 1851
CPU Main Features64 bit 18-Core Processor
GPU/VGA TypeNVIDIA GeForce RTX 5080
GPU Memory16GB GDDR7
Graphics CardGeForce RTX 5080
Graphics InterfacePCI Express x16
Virtual Reality ReadyYes
Memory Capacity32GB DDR5
Memory SpeedDDR5
Memory Slot (Total)4
Memory Slots (Available/Total)4
SSD4TB NVMe
Storage Spec4TB SSD
Screen SizeNo Screen
WLANWi-Fi 7
WiFi GenerationWi-Fi 7
BluetoothBluetooth v5.4
Front USB1
Video Ports1 x HDMI 2.1b, 3 x DisplayPort 2.1b
Rear USB5
RJ451 port
Package TypeRetail

Other versions of this model

5 more in the same range

Same family, different memory, cooler or clock — compare before you commit.

Questions about this item

Will the 360 mm liquid cooler fit in a standard ATX case?

The cooler is built into the MSI MAG PANO M100R chassis, so no separate mounting is required.

What is the first step when installing the pre-applied liquid cooling on the Core Ultra 5 250KF?

The system ships with the 360 mm loop already filled and tested; simply connect power and press the front button.

When should the 360 mm liquid cooler be serviced or the coolant replaced?

The sealed loop is maintenance-free for the life of the PC; no user refill or service interval is needed.

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