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Silver rectangular rack-mount server chassis with eight 2.5-inch drive bays visible on the front panel

HPE

HPE ProLiant ML350 Gen10 8SFF rack server 2x Xeon Silver 4214 384GB DDR4

SKU CH-25TA-51RGS

Dual Xeon Silver 4214 processors at 2.2GHz with 384GB DDR4 ECC memory in an 8-bay 2.5-inch chassis, Smart Array P408 SAS controller and dual 500W power supplies

  • TypeRack
  • CPU TypeIntel Xeon
  • CPU Speed2.2GHz
  • # of Processors Installed2
  • MAX Processors2
  • Installed Memory Size384GB
  • Dual 12-core Xeon Silver 4214 CPUs deliver 24 threads at 2.2GHz
  • 384GB DDR4 ECC registered memory supports large workloads
  • HPE Smart Array P408 SAS controller manages up to 8 drive bays
  • Integrated Intel I350/X540 network card provides 2x 10GbE and 2x 1GbE ports
  • Dual 500W Flex Slot power supplies with HPE iLO Advanced remote management

Dual Xeon 4214 tower server

The HPE ProLiant ML350 Gen10 chassis arrives with two Intel Xeon Silver 4214 processors running at 2.2 GHz, each offering 12 cores and 16.5 MB cache. It is built for businesses that need a rack-mountable platform with up to eight 2.5‑inch drive bays and integrated remote management through HPE iLO Advanced.

384 GB DDR4 memory upgrade path

The system ships with 384 GB of DDR4 ECC registered memory installed and supports a maximum of 3 TB, so the jump is worth it when workloads outgrow the factory capacity. The Smart Array P408 SAS controller handles the storage layer, and no drives are included, letting you choose the exact capacity and redundancy you require.

Tool-less rail installation notes

The 36 × 24 × 10 in rack unit weighs 40 lb and fits standard rails that are available on request, while dual 500 W Flex Slot power supplies provide redundancy. Common issues include forgetting to populate all memory channels for optimal bandwidth and overlooking the need to order drive carriers separately for the 8 SFF bays.

Highlights

  • Dual 12-core Xeon Silver 4214 CPUs deliver 24 threads at 2.2GHz
  • 384GB DDR4 ECC registered memory supports large workloads
  • HPE Smart Array P408 SAS controller manages up to 8 drive bays
  • Integrated Intel I350/X540 network card provides 2x 10GbE and 2x 1GbE ports
  • Dual 500W Flex Slot power supplies with HPE iLO Advanced remote management

Specifications

BrandHP
SeriesProLiant
ModelRack Mount
TypeRack
CPU TypeIntel Xeon
CPU Speed2.2GHz
# of Processors Installed2
MAX Processors2
Installed Memory Size384GB
Memory TypeDDR4
Max Memory Capacity3TB
Hard Drive (Installed)4.800,00
Storage ControllerHPE Smart Array P408 SAS Controller
HDD InterfaceSAS
GPU TypeIntegrated Graphics
Remote ManagementHPE iLO Advanced
Dimensions36 x 24 x 10 in
Weight40

Questions about this item

What are the exact chassis dimensions I must clear in my rack for this ML350 Gen10?

The unit measures 36 inches deep, 24 inches wide and 10 inches high; plan for that envelope plus cable routing space.

How do I install the Xeon Silver 4214 processors and 384GB DDR4 memory without damaging the sockets?

Align each processor with the socket triangle, lower the load plate gently, then seat DDR4 ECC registered DIMMs in the prescribed channel order until the ejectors click.

Which components will need replacement first in the Smart Array P408 storage path?

The two 500W flex-slot power supplies and the SAS drive backplane are the primary field-replaceable units; the P408 controller and iLO module rarely fail.

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