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Rectangular ATX motherboard in dark grey with silver heatsinks and black slots

MSI

MSI PRO B850-S WIFI6E AMD motherboard

SKU CH-GDHK-6WE9C MPN PRO B850-S WIFI6E

ATX motherboard with AM5 socket, AMD B850 chipset, DDR5 up to 8200 MT/s, PCIe 5.0 M.2, 2.5G LAN and Wi-Fi 6E

  • CPU Socket TypeAM5
  • CPU TypeRyzen 7000 Series / Ryzen 8000 Series / Ryzen 9000 Series
  • ChipsetAMD B850
  • Number of Memory Slots4x288pin (DDR5)
  • Memory StandardSupport DDR5 8200 - 5600 (OC) MT/s / 5600 - 4800 (JEDEC) MT/
  • Maximum Memory Supported256GB

Option PRO B850-S WIFI6E

Struck-through versions exist but are not stocked here.

  • Supports AMD Ryzen 9000, 8000 and 7000 series processors via AM5 socket
  • DDR5 memory up to 8200 MT/s overclocked across four slots with 256 GB maximum capacity
  • PCIe 5.0 x4 M.2 slot from CPU for fastest storage performance
  • 5G LAN and Wi-Fi 6E provide high-speed wired and wireless networking
  • 12+2+1 Duet Rail power system with 7 W/mK thermal pads keeps VRM cool under load

Socket AM5 for Ryzen 7000 8000 9000

The MSI PRO B850-S WIFI6E is an ATX motherboard built on the AMD B850 chipset for Socket AM5 processors. It supports Ryzen 7000 8000 and 9000 series CPUs with a 12 Duet Rail power system using P-PAK components and dual 8-pin CPU power connectors. Four DDR5 slots accept up to 256 GB running at 8200 MT/s OC with AMD EXPO profiles.

EZ M.2 Clip II and EZ PCIe Clip II

Tool-free latches secure M.2 drives and the primary PCIe 4.0 x16 graphics card without screws. The primary M.2 slot runs at PCIe 5.0 x4 from the CPU and accepts 22110 and 2280 lengths; a second CPU-linked slot runs at PCIe 4.0 x4 for 2280 and 2260 drives. A chipset-linked PCIe 4.0 x4 slot and a PCIe 3.0 x1 slot provide additional expansion.

Check CPU generation for lane allocation

Ryzen 9000 and 7000 series deliver PCIe 4.0 x16 on the top slot while Ryzen 8700 8600 8400 series operate at x8. Verify your cooler clears the VRM heatsink and 7 W/mK thermal pads. Ensure the power supply provides two 8-pin CPU connectors. The board includes 2.5G LAN Wi-Fi 6E Realtek ALC897 audio four SATA 6Gb/s ports and RAID support for SATA and M.2 NVMe arrays.

Highlights

  • Supports AMD Ryzen 9000, 8000 and 7000 series processors via AM5 socket
  • DDR5 memory up to 8200 MT/s overclocked across four slots with 256 GB maximum capacity
  • PCIe 5.0 x4 M.2 slot from CPU for fastest storage performance
  • 5G LAN and Wi-Fi 6E provide high-speed wired and wireless networking
  • 12+2+1 Duet Rail power system with 7 W/mK thermal pads keeps VRM cool under load

Specifications

BrandMSI
ModelPRO B850-S WIFI6E
CPU Socket TypeAM5
CPU TypeRyzen 7000 Series / Ryzen 8000 Series / Ryzen 9000 Series
ChipsetAMD B850
Number of Memory Slots4x288pin (DDR5)
Memory StandardSupport DDR5 8200 - 5600 (OC) MT/s / 5600 - 4800 (JEDEC) MT/s
Maximum Memory Supported256GB
Channel SupportedDual Channel
Memory Performance ProfileAMD EXPO
ECC SupportedNon-ECC
Buffer SupportedUn-buffered
Memory FeatureSupports CUDIMM, Clock Driver bypass mode only
PCI Express 4.0 x16PCI_E1 Gen PCIe 4.0 supports up to x16 (From CPU)
PCI_E1 slot
- Supports PCIe 4.0 x16 (For Ryzen 9000/ 7000 Series processors)
- Supports PCIe 4.0 x8 (For Ryzen 8700/ 8600/ 8400 Series processors)
- Supports PCIe 4.0 x4 (For Ryzen 8500/ 8300 Series processor)
PCI Express x4PCI_E3 Gen PCIe 4.0 supports up to x4 (From Chipset)
PCI Express x1PCI_E2 Gen PCIe 3.0 supports up to x1 (From Chipset)
Serial ATA (SATA)4 x SATA 6Gb/s
M.2M.2_1 Source (From CPU) supports up to PCIe 5.0 x4 , supports 22110/2280 devices
M.2_2 Source (From CPU) supports up to PCIe 4.0 x4 , supports 2280/2260 devices
M2_1 slot
- Supports up to PCIe 5.0 x4 (For Ryzen 9000/ 7000 Series processors)
- Supports up to PCIe 4.0 x4 (For Ryzen 8000 Series processors)
M2_2 slot
- Supports up to PCIe 4.0 x4 (For Ryzen 9000/ 8700/ 8600/ 8400/ 7000 Series processors)
- Supports up to PCIe 4.0 x2 (For Ryzen 8500/ 8300 Series processors)
SATA RAIDSupports RAID 0, RAID 1, and RAID 10 for SATA storage devices
Supports RAID 0 and RAID 1 for M.2 NVMe storage devices
Audio ChipsetRealtek ALC897
Audio Channels7.1 Channels
Max LAN Speed2.5Gbps
Wireless LANWi-Fi 802.11 ax
BluetoothBluetooth 5.3
Back I/O PortsClear CMOS Button
1 x DisplayPort
1 x 2.5G LAN
1 x USB 10Gbps Type-A
4 x USB 5Gbps Type-A
2 x Wi-Fi / Bluetooth
3 x Audio Connectors
Flash BIOS Button
1 x HDMI
2 x USB 10Gbps Type-A
1 x USB 10Gbps Type-C
Onboard USB4 x USB 2.0 ports
2 x USB 5Gbps Type A ports
1 x USB 10Gbps Type C ports
Other Connectors1 x CPU Fan
1 x Combo Fan (Pump_Sys Fan)
4 x System Fan
2 x Front Panel (JFP)
1 x Chassis Intrusion (JCI)
1 x Front Audio (JAUD)
1 x Com Port (JCOM)
1 x Tuning Controller connector(JDASH)
3 x Addressable V2 RGB LED connector (JARGB_V2)
1 x RGB LED connector(JRGB)
1 x TPM pin header(Support TPM 2.0)
Form FactorATX
LED Lighting4 x EZ Debug LED
1 x EZ Memory Detection LED
Dimensions (W x L)12.0" x 9.6"
Power Pin1 x Power Connector(ATX_PWR)
2 x Power Connector(CPU_PWR)
Windows 11Supported
Shipping weight1.45 kg
Package size343 × 274 × 76 mm

Other versions of this model

5 more in the same range

Same family, different memory, cooler or clock — compare before you commit.

Questions about this item

How do I confirm the PRO B850-S WIFI6E is running DDR5 at the advertised 8200 MT/s after build?

Enter the BIOS and enable the AMD EXPO profile for your memory kit; the memory tab will then show the active speed at 8200 MT/s or the highest supported OC frequency for the installed modules.

What ships with the PRO B850-S WIFI6E and which key items are not included?

The box contains the ATX motherboard, I/O shield, Wi-Fi 6E antenna, SATA cables, EZ M.2 Clip II, EZ PCIe Clip II and documentation; CPU, DDR5 memory, M.2 NVMe drives, graphics card, power supply and chassis must be purchased separately.

Which M.2 slot should I use for a PCIe 5.0 NVMe drive on this board?

Install the drive in the M.2_1 slot sourced from the CPU; it supports PCIe 5.0 x4 and 22110 or 2280 form factors, while M.2_2 is limited to PCIe 4.0 x4.

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